Gene-ius

Question:

When given a DNA coding sequence, are the fifth graders required to transcribe that into RNA before translating that again (using RNA) in order to find the sequence needed to find the different proteins?
For example, if they’re given the sequence TAC GCC ACT, can they use the codon table to translate into amino acids directly from AUG CGG UGA, or do they have to go an additional step and translate AUG CGG UGA into UTC GCC ACU, before going to the amino acids? Sorry for any confusion!

 

Answer:

Fifth grade teams should understand the relationship and transfer of information from DNA to RNA to amino acid sequence.  All information provided would contain the relevant information needed such as directionality of the sequence (5’ to 3’ or 3’ to 5’) or template vs coding stand.  If asked to provide the RNA sequence, they would need to provide the correct RNA sequence as produced from transcription from the template strand. In the example provided in the question, the RNA sequence, UTC GCC ACU, would not be the correct answer assuming the original DNA sequence, TAC GCC ACT, is the template strand (3’ to 5”).  The only correct RNA sequence would be AUG CGG UGA.  The codon table in the study guide will also be used during the event and is DNA to amino acids, so they will have to read the code from the DNA coding strand.